Screening of Dipeptides Having Central Functions for Excitation and Sedation

Author(s): H. Yamane , D. M. Denbow , M. Furuse .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 3 , 2009

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Abstract:

The naturally-occurring dipeptide carnosine (β-alanyl-L-histidine) and the tripeptide glutathione (L-γglutamyl- L-cysteinylglycine) are found extensively in animal tissues such as brain and skeletal muscle. Central functions for excitation and sedation of them and their derivatives were screened.

Keywords: Dipeptides, carnosine, glutathione, excitation, sedation

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Article Details

VOLUME: 9
ISSUE: 3
Year: 2009
Page: [300 - 305]
Pages: 6
DOI: 10.2174/1389557510909030300
Price: $58

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