New Potential Targets to Modulate Neutrophil Function in Inflammation

Author(s): R. A. Burgos, M. A. Hidalgo, C. D. Figueroa, I. Conejeros, J. L. Hancke.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 9 , Issue 2 , 2009

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Abstract:

The importance of neutrophils in human disease such as rheumatoid arthritis, asthma, adult respiratory distress syndrome, and COPD has prompted the search for drugs capable to slow down neutrophil-dependent inflammation, without interference with innate immune responses. In this review, we summarize new potential drugs targets against neutrophils mediated inflammatory responses.

Keywords: Neutrophil, drugs, innate immunity, inflammation

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Article Details

VOLUME: 9
ISSUE: 2
Year: 2009
Page: [153 - 168]
Pages: 16
DOI: 10.2174/138955709787316092
Price: $58

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