Recent Patents on Cardiovascular Drug Discovery (Discontinued)


Patents in the Diagnosis and Therapy of Neurocardiogenic Syncope

Author(s): Anna Kostopoulou, Efthimios G. Livanis and Vassilis Voudris

Affiliation: Onassis Cardiac Surgery Center, 2nd Dept. of Cardiology, 356 Syngrou Ave, 17674 Athens, Greece.


Neurocardiogenic syncope is one of the most common types of syncope, characterized by arterial vasodilatation with or without bradycardia. The regulation of blood pressure and heart rate is the result of a complex reaction between the central and peripheral nervous system with the circulatory system. Multiple therapies, pharmaceutical and interventional, have been applied without any proven effect. The initial positive reports on pacing were not demonstrated in enough number of controlled studies. Neurocardiogenic syncope continues to remain a clinical problem in terms of understanding its underlying mechanisms and therapy needs to be enlightened by future studies. This article provides a background of diagnosis and therapy of neurocardiogenic syncope and reviews some related patents.

Keywords: Syncope, neurocardiogenic, implanted loop recorders, treatment, pacemakers

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Article Details

Page: [67 - 71]
Pages: 5
DOI: 10.2174/157489009787259973