Abstract
In this paper the physiological role of NO and isoforms of NOS in the gastrointestinal tract and the involvement of NO in pathological processes of digestive tract as well as the perspective of therapeutic use of NO-donating drugs and selective inhibitors of phosphodiesterase in the treatment of gastric diseases were presented.
Keywords: Nitric oxide, constitutive nitric oxide synthase, inducible nitric oxide synthase, gastrointestinal tract, inflammatory process, malignant transformations, NO-donor drugs, phosphodiesterase inhibitors
Mini-Reviews in Medicinal Chemistry
Title: Role of Nitric Oxide in Physiology and Pathology of the Gastrointestinal Tract
Volume: 8 Issue: 14
Author(s): A. Stanek, A. Gadowska-Cicha, K. Gawron, T. Wielkoszynski, B. Adamek, G. Cieslar, A. Wiczkowski and A. Sieron
Affiliation:
Keywords: Nitric oxide, constitutive nitric oxide synthase, inducible nitric oxide synthase, gastrointestinal tract, inflammatory process, malignant transformations, NO-donor drugs, phosphodiesterase inhibitors
Abstract: In this paper the physiological role of NO and isoforms of NOS in the gastrointestinal tract and the involvement of NO in pathological processes of digestive tract as well as the perspective of therapeutic use of NO-donating drugs and selective inhibitors of phosphodiesterase in the treatment of gastric diseases were presented.
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Cite this article as:
Stanek A., Gadowska-Cicha A., Gawron K., Wielkoszynski T., Adamek B., Cieslar G., Wiczkowski A. and Sieron A., Role of Nitric Oxide in Physiology and Pathology of the Gastrointestinal Tract, Mini-Reviews in Medicinal Chemistry 2008; 8 (14) . https://dx.doi.org/10.2174/138955708786786462
DOI https://dx.doi.org/10.2174/138955708786786462 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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