Apoptotic Signaling Pathways as a Target for the Treatment of Liver Diseases

Author(s): J. L. Mauriz, M. J. Tunon, J. Gonzalez-Gallego.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 14 , 2008

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Abstract:

Dysregulation of apoptosis is a major contributor to the initiation and aggravation of liver injury. Agents that modulate apoptosis may be of therapeutic benefit in a number of liver diseases, and research related to cell type-specific activation or inhibition of apoptotic signaling pathways will provide new strategies for treatment.

Keywords: Liver, hepatitis, alcohol, hepatocarcinoma, cholestasis, fulminant hepatic failure, steatohepatitis, fibrosis

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Article Details

VOLUME: 8
ISSUE: 14
Year: 2008
Page: [1485 - 1493]
Pages: 9
DOI: 10.2174/138955708786786499
Price: $58

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