Mini-Reviews in Medicinal Chemistry


Flavonoids: Prospective Drug Candidates

Author(s): Luisa Helena Cazarolli, Leila Zanatta, Elga Heloisa Alberton, Maria Santos Reis Bonorino Figueiredo, Poliane Folador, Rosangela Guollo Damazio, Moacir Geraldo Pizzolatti and Fatima Regina Mena Barreto Silva

Affiliation: Departamento de Bioquimica, Centro de Ciencias Biologicas, Campus Universitario, UFSC. Bairro Trindade. Cx. Postal 5069, CEP: 88040-970, Florianopolis, SC, Brazil.


The purpose of this review is to discuss the recent developments related to the chemistry and medicinal properties of flavonoids. Major flavonoids that show well categorized structures and well defined structure functionrelationships are: flavans, flavanones, flavones, flavanonols, flavonols, catechins, anthocyanidins and isoflavone. The biological properties of flavonoids include antioxidant, anti-inflamatory, antitumoral, antiviral and antibacterial, as well as a direct cytoprotective effect on coronary and vascular systems, the pancreas and the liver. These characteristics place them among the most attractive natural substances available to enrich the current therapy options.

Keywords: Flavonoids, medicinal properties, absorption, disease

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Article Details

Page: [1429 - 1440]
Pages: 12
DOI: 10.2174/138955708786369564
Price: $58