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Mini-Reviews in Medicinal Chemistry
ISSN (Print): 1389-5575
ISSN (Online): 1875-5607
VOLUME: 8
ISSUE: 12
DOI: 10.2174/138955708786141034      Price:  $58









Chalcones and their Potential Role in Inflammation

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Author(s): C. Kontogiorgis, M. Mantzanidou and D. Hadjipavlou-Litina
Pages 1224-1242 (19)
Abstract:
Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.
Keywords:
Natural/synthetic chalcones, inflammation, anti-inflammatories, antioxidants
Affiliation:
Aristotle University of Thessaloniki, School of Pharmacy, Department of Pharmaceutical Chemistry, 54124, Greece.