Antimicrobial Peptide Preferential Binding of E. coli O157:H7

Author(s): Jason W. Soares, Romy Kirby, Kimberly M. Morin, Charlene M. Mello.

Journal Name: Protein & Peptide Letters

Volume 15 , Issue 10 , 2008

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Abstract:

The studies presented here explore antimicrobial peptide preferential binding behavior for a target pathogen, Escherichia coli O157:H7. A modified immunoassay and surface plasmon resonance were employed to evaluate immobilized peptide binding of whole bacterial cells. The knowledge gained may guide the rational design of peptides with enhanced species binding selectivity.

Keywords: Antimicrobial peptide, E. coli O157:H7, preferential binding, molecular recognition, whole cell binding, surface plasmon resonance

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Article Details

VOLUME: 15
ISSUE: 10
Year: 2008
Page: [1086 - 1093]
Pages: 8
DOI: 10.2174/092986608786071049
Price: $58

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