The studies presented here explore antimicrobial peptide preferential binding behavior for a target pathogen, Escherichia coli O157:H7. A modified immunoassay and surface plasmon resonance were employed to evaluate immobilized peptide binding of whole bacterial cells. The knowledge gained may guide the rational design of peptides with enhanced species binding selectivity.
Keywords: Antimicrobial peptide, E. coli O157:H7, preferential binding, molecular recognition, whole cell binding, surface plasmon resonance
Rights & PermissionsPrintExport