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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Antimicrobial Peptide Preferential Binding of E. coli O157:H7

Author(s): Jason W. Soares, Romy Kirby, Kimberly M. Morin and Charlene M. Mello

Volume 15, Issue 10, 2008

Page: [1086 - 1093] Pages: 8

DOI: 10.2174/092986608786071049

Price: $65

Abstract

The studies presented here explore antimicrobial peptide preferential binding behavior for a target pathogen, Escherichia coli O157:H7. A modified immunoassay and surface plasmon resonance were employed to evaluate immobilized peptide binding of whole bacterial cells. The knowledge gained may guide the rational design of peptides with enhanced species binding selectivity.

Keywords: Antimicrobial peptide, E. coli O157:H7, preferential binding, molecular recognition, whole cell binding, surface plasmon resonance


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