Title: Microwave-Assisted Synthesis of 3-substituted 2-iminopyrido[2,3-e][1,3] oxazin-4-ones
VOLUME: 5 ISSUE: 7
Author(s):Thomas Kurz and Miriam K. Pein
Affiliation:Heinrich-Heine University, Institute of Pharmaceutical and Medicinal Chemistry, Universitaetsstr. 1, 40589 Duesseldorf, Germany.
Keywords:Microwave-assisted synthesis, 2-imino-pyrido[2,3-e][1,3]oxazin-4-ones, cyanogen bromide, 3-hydroxy-picolinic acid derivatives
Abstract: The rapid microwave-assisted preparation of 3-substituted 2-imino-pyrido[2,3-e][1,3]oxazin-4-ones starting from N-aralkoxy-3-hydroxy-pyridine-2-carboxamides, 3-hydroxy-pyridine-2-carboxamides or 3-hydroxy-pyridine-2- carboxylic acid hydrazides and cyanogen bromide is described.
