Palladium-Catalyzed Cross-Couplings of 2-Tributylstannyl-N-Boc-2,3- Dehydropiperidine, a Cyclic Enecarbamate

Author(s): Alessandro B.C. Simas, Daniel L. de Sales, Samir F.A. Cavalcante, Cristina M. de Medeiros, Sandro H.S. Moraes, Erika M. de Carvalho.

Journal Name: Letters in Organic Chemistry

Volume 5 , Issue 7 , 2008

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Cross-couplings of 2-tributylstannyl-N-Boc-2,3-dehydropiperidine, a six-membered cyclic enecarbamate, with aryl iodides and triflates are reported for the first time. Under the Pd(0)/AsPh3 catalytic system (Farinas conditions), better conversions of this challenging substrate into the expected products were achieved with shorter reactions carried out under higher temperature.

Keywords: Stille coupling, piperidine, synthesis, heterocycle, cyclic amine, Umpolung

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Article Details

Year: 2008
Page: [587 - 590]
Pages: 4
DOI: 10.2174/157017808785982149
Price: $65

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