Synthesis and Anticancer Evaluation of some Newer 2, 5-Disubstituted-1,3, 4-Oxadiazole Analogues

Author(s): Rakesh R. Somani, Prabhakar Y. Shirodkar, Vilasrao J. Kadam.

Journal Name: Letters in Drug Design & Discovery

Volume 5 , Issue 6 , 2008

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Abstract:

A series of some newer 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives (5a-5j) were synthesized and evaluated for anticancer activity. Compound 5f showed excellent activity in majority of the cell lines.

Keywords: 2,5-Disubstituted-1,3,4-oxadiazole, Schiff's bases, 4-Thiazolidinone derivatives, Anticancer activity

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Article Details

VOLUME: 5
ISSUE: 6
Year: 2008
Page: [364 - 368]
Pages: 5
DOI: 10.2174/157018008785777360
Price: $65

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