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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Simple and Convenient Synthesis of (±)-Bakuchiol

Author(s): Hongli Chen and Yuanchao Li

Volume 5, Issue 6, 2008

Page: [467 - 469] Pages: 3

DOI: 10.2174/157017808785740499

Price: $65

Abstract

A simple and convenient synthesis of (±)-bakuchiol has been developed. The key intermediate was obtained in only one step from the easily available starting material, citral, by an 1,4-addition procedure. (±)-Bakuchiol was finally produced in 4 steps to give 50% overall yield.

Keywords: (±)-Bakuchiol, citral, 1,4-addition, Grignard reagent


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