Lanthanide(III) Chelates for Selective Solution Phase Labeling of Biomolecules

Author(s): Janne Ketola, Lassi Jaakkola, Jari Hovinen.

Journal Name: Letters in Organic Chemistry

Volume 5 , Issue 6 , 2008

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Abstract:

Synthesis of photoluminescent lanthanide(III) chelates that allow selective solution phase labeling of bioactive molecules using phosphate elimination, native chemical ligation, and ‘click-chemisty’ is described.

Keywords: Native chemical ligation, phosphate elimination, ‘click chemistry’, lanthanide(III) chelates, labeling

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Article Details

VOLUME: 5
ISSUE: 6
Year: 2008
Page: [444 - 449]
Pages: 6
DOI: 10.2174/157017808785740462
Price: $65

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