Letters in Drug Design & Discovery

G. Perry
University of Texas
San Antonio, TX
USA
Email: lddd@benthamscience.org

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Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited

Author(s): Dane M. Springer, Jason T. Goodrich, Bing-Yu Luh, Joanne J. Bronson, Qi Gao, Stella Huang, Kenneth DenBleyker, Thomas J. Dougherty, Joan Fung-Tomc.

Abstract:

Pleuromutilin derivatives comprised of varied core structures have been synthesized. Many of the compounds described were found to have surprisingly good antibacterial activity in vitro.

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Article Details

VOLUME: 5
ISSUE: 5
Year: 2008
Page: [327 - 331]
Pages: 5
DOI: 10.2174/157018008784912063
Price: $58