Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review

Author(s): Sara Mazzucco, Andrea Cipriani, Corrado Barbui, Salvatore Monaco.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 8 , 2008

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Abstract:

Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and nonrandomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.

Keywords: Neuroleptics, typical antipsychotics, atypical antipsychotics, dopamine, dementia, cerebrovascular events

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Article Details

VOLUME: 8
ISSUE: 8
Year: 2008
Page: [776 - 783]
Pages: 8
DOI: 10.2174/138955708784912175
Price: $58

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