Computational Analyses of TBC Protein Family in Eukaryotes

Author(s): Xinjiao Gao, Changjiang Jin, Yu Xue, Xuebiao Yao.

Journal Name:Protein & Peptide Letters

Volume 15 , Issue 5 , 2008

Abstract:

Tre-2/Bub2/Cdc16 domain-containing proteins (TBC proteins) participate in wide range cellular processes. With computational approaches, 137 non-redundant TBC proteins from five model organisms were identified and classified into 13 subfamilies base on molecular evolutionary tree. This phylogenetic analysis provides useful functional annotation of newly-identified TBC proteins and guides for further experimentation.

Keywords: TBC domain, phylogenetic tree, USP6, polarized exocytosis, cell cycle, cytokinesis

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Article Details

VOLUME: 15
ISSUE: 5
Year: 2008
Page: [505 - 509]
Pages: 5
DOI: 10.2174/092986608784567483
Price: $58