Chemistry of Norbornane/ene and Heteronorbornane/ene β-Amino Acids

Author(s): Ferenc Csende, Ferenc Fulop, Geza Stajer.

Journal Name: Current Organic Synthesis

Volume 5 , Issue 2 , 2008

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Abstract:

The structures, biological properties, preparations and synthetic applications of norbornane/ene bicyclic and heteroatombridged β-amino acids are discussed. These compounds are rare and unique β-alanine derivatives which can be used as bifunctional synthons for the preparation of heterocycles. Through peptidation, they form oligopeptide-like molecules with special helical structures.

Keywords: (Hetero)bicyclic β-amino acids, biological activity, heterocycles, retro diels-alder reactions, ugi reactions, peptide syntheses

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Article Details

VOLUME: 5
ISSUE: 2
Year: 2008
Page: [173 - 185]
Pages: 13
DOI: 10.2174/157017908784221576
Price: $58

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