The structures, biological properties, preparations and synthetic applications of norbornane/ene bicyclic and heteroatombridged β-amino acids are discussed. These compounds are rare and unique β-alanine derivatives which can be used as bifunctional synthons for the preparation of heterocycles. Through peptidation, they form oligopeptide-like molecules with special helical structures.
Keywords: (Hetero)bicyclic β-amino acids, biological activity, heterocycles, retro diels-alder reactions, ugi reactions, peptide syntheses
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