Synthesis and Characterization of Two Novel Stigmasterol-Based Cationic Lipids

Author(s): Jia Qian, Zhiping Le, Fei Yu, Pinghan Jiang.

Journal Name: Letters in Organic Chemistry

Volume 5 , Issue 4 , 2008

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Abstract:

Two novel stigmasterol-based cationic lipids, Stigmasta-5,22-dien-3-ol,4-[[2- (dimethylamino)ethyl]amino]-4- oxobutanoate,(3β,22E)-(9CI) and stigmasta-5,22-dien- 3-ol,4-[[2-(dimethylamino)ethyl]amino](2E)-4-oxobutenoate, (3β,22E)-(9CI), were synthesized. These compounds were characterized by mass spectrometry (MS), nuclear magnetic resonance (NMR) and fourier transform infrared (FT-IR).

Keywords: Cationic lipids, stigmasterol, synthesis, characterization

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Article Details

VOLUME: 5
ISSUE: 4
Year: 2008
Page: [313 - 315]
Pages: 3
DOI: 10.2174/157017808784049461
Price: $58

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