New Agents to Treat Life-Threatening Fungal Infections

Author(s): Pauline C. Ting, Scott S. Walker.

Journal Name: Current Topics in Medicinal Chemistry

Volume 8 , Issue 7 , 2008

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Abstract:

Fungi can cause life threatening diseases, particularly in patients with weakened immune systems. While treatment options are available for these individuals, dose limiting toxicity and the appearance of drug resistant organisms are growing problems. Therefore, the identification, development, and registration of new, safe, and efficacious agents are needed. Herein, we review recent developments in the field of antifungal drug discovery. We focus on recently launched drugs (triazoles and echinocandins), agents in clinical development, and compounds in discovery.

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Article Details

VOLUME: 8
ISSUE: 7
Year: 2008
Page: [592 - 602]
Pages: 11
DOI: 10.2174/156802608783955610
Price: $58

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