Current Topics in Medicinal Chemistry

Allen B. Reitz
Fox Chase Chemical Diversity Center, Inc.
Doylestown, PA


Vaccines Against Cysticercosis

Author(s): Edda Sciutto, Gladis Fragoso, Aline S. de Aluja, Marisela Hernandez, Gabriela Rosas and Carlos Larralde

Affiliation: Instituto de Investigaciones Biomedicas, A.P. 70228; 04510 Mexico, D. F., Mexico Mexico 04510,D.F.; Mexico.


Taenia solium cysticercosis is a major parasitic disease that seriously and frequently affects human health and economy in undeveloped countries. Since pigs are an indispensable intermediate host, it is conceivable to curb transmission by reducing pig cysticercosis through their effective vaccination. This article reviews current knowledge on the development vaccines against porcine cysticercosis. It highlights the development of several versions of S3Pvac aimed to increase effectiveness, reduce costs and increase feasibility by novel delivery systems and alternative routes of administration.

Keywords: Taenia solium, cysticercosis, neurocysticercosis, vaccines, control

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Article Details

Page: [415 - 423]
Pages: 9
DOI: 10.2174/156802608783790839
Price: $58