Malaria Combination Therapies: Advantages and Shortcomings

Author(s): A. Martinelli , R. Moreira , P. V.L. Cravo .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 3 , 2008

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Abstract:

Drug combination therapies have been devised to delay the development and spread of resistant malaria parasites. However, poor design often leads to ineffective combinations. Here, the properties of various drug combinations are reviewed in relationship to drug resistance and their pharmacokinetic compatibility.

Keywords: Malaria, drug resistance, drug combination therapy, artemisinin, quinolines, antifolates

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Article Details

VOLUME: 8
ISSUE: 3
Year: 2008
Page: [201 - 212]
Pages: 12
DOI: 10.2174/138955708783744092
Price: $58

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