An Efficient One-Pot, Two-Step Synthesis of Cyclobuxophyllinine M from Cyclovirobuxine D in Aqueous Media

Author(s): Min Ji, Hai-Feng Liu, Xiao-Qing Wu, Yan-Bing Duan, Bin Gu.

Journal Name: Letters in Organic Chemistry

Volume 5 , Issue 2 , 2008

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Abstract:

A highly efficient one-pot, two-step sequential process consisting of modified Jones oxidation of aqueous cyclovirobuxine D acetate followed by Ruschig degradation after pH regulation with saturated aqueous NaOH, provided cyclobuxophyllinine M in high yield and in a single geometrical isomeric form.

Keywords: Jones oxidation, Ruschig degradation, cyclobuxophyllinine M, cyclovirobuxine D, aqueous media

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Article Details

VOLUME: 5
ISSUE: 2
Year: 2008
Page: [140 - 141]
Pages: 2
DOI: 10.2174/157017808783743920
Price: $58