In Situ Synthesis of Benzyl Chloromethyl Ether and its Use for the Protection and Deprotection of Bifunctional Hydroxyl Compounds

Author(s): Javid H. Zaidi, Khalid M. Khan, Sadullah Mir, Naseem Iqbal Gunjial, M. Arfan.

Journal Name: Letters in Organic Chemistry

Volume 5 , Issue 2 , 2008

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Abstract:

In situ synthesis of benzyl chloromethyl ether and its use to protect bifunctional hydroxyl compounds as benzyloxymethyl ethers is reported. This methodology was extended to alkylate the N-protected L-amino acids.

Keywords: Benzyl chloromethyl ether, protection, deprotection

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Article Details

VOLUME: 5
ISSUE: 2
Year: 2008
Page: [125 - 127]
Pages: 3
DOI: 10.2174/157017808783743894
Price: $58

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