Title: Solvent-Free Amination of Heteroaromatic Chlorides
VOLUME: 5 ISSUE: 2
Author(s):Erwan Le Gall, Stephane Sengmany, Corinne Gosmini, Jacques Perichon and Pascal Retailleau
Affiliation:Electrochimie et Synthese Organique group, Institut de Chimie et des Materiaux Paris Est, ICMPE CNRS, 2-8 rue Henri Dunant, 94320 Thiais, France.
Keywords:Amination, heteroaromatic chlorides, solvent-free reaction
Abstract: The coupling of 5-membered heterocyclic amines such as pyrazole and imidazole derivatives with heteroaromatic chlorides like 4,7-dichloroquinoline, 2-chlorobenzoxazole and 2-chlorobenzothiazole has been realized in good yields using very simple solvent-free conditions.
