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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Indium Trichloride Catalysed Imino Diels-Alder Reaction of Imesatins: A Facile Synthesis of Novel Spirooxindole 1H – pyrano[2,3-c ]quinolines

Author(s): R. Raghunathan, E. Ramesh and E. Elamparuthi

Volume 5, Issue 2, 2008

Page: [82 - 86] Pages: 5

DOI: 10.2174/157017808783743948

Price: $65

Abstract

A novel method for the construction of spirooxindole via imino Diels-Alder reaction of in situ generated isatin imine with dihydropyran is reported. InCl3 efficiently catalyzes the reaction to afford cis- and trans-diastereisomers in fairly good yields.

Keywords: Indium chloride, imino Diels-Alder reaction, isatin, tetrahydroquinoline, spirooxindole


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