Essential Factors for Successful Virtual Screening
Markus H.J. Seifert,
Virtual high-throughput screening (vHTS) is a powerful technique for identifying hit molecules as starting points for medicinal chemistry. Numerous successful applications of vHTS have been published using a large variety of methodologies. This review attempts to identify the essential factors for successful virtual screening in the hit identification phase.
Keywords: Virtual screening, high-throughput screening, docking, scoring, hit identification, similarity search
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