Proteomic Analysis of Liver Diseases: Molecular Mechanisms and Biomarker Discovery

Author(s): Fernando J. Corrales, Enrique Santamaria, Javier Munoz, Joaquin Fernandez-Irigoyen, Laura Sesma, Leticia Odriozola.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 8 , Issue 1 , 2008

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Abstract:

Liver diseases afflict more than 10% of the world population. Although the main risk factors are known and the population at risk is monitored, new biomarkers are urgently needed to allow early diagnosis and hence more effective therapeutic interventions. Here, we revise the contribution of proteomics to the study of liver diseases and its potential impact in the clinical practice is evaluated.

Keywords: Proteomics, mass spectrometry, liver diseases, biomarkers

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Article Details

VOLUME: 8
ISSUE: 1
Year: 2008
Page: [1 - 9]
Pages: 9
DOI: 10.2174/138955708783331595

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