The Modular Synthesis of Chiral N-Heterocyclic Carbene Precursors

Author(s): Attila Paczal, Andras Kotschy.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 8 , 2007

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A series of chiral N-heterocyclic carbene precursors based on the dihydroimidazole framework were prepared from easily available chiral amines. The sequential attachment of these amines and mesitylamine to chloroacetyl chloride followed by reduction and subsequent ring closure gave the desired dihydroimidazolium salts in good yield.

Keywords: Heterocyclic carbenes, chirality, chiral amines, ring closure, imidazolium salts

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Article Details

Year: 2007
Page: [563 - 566]
Pages: 4
DOI: 10.2174/157017807782795565
Price: $65

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