Total Synthesis of (±)-Euryfuran Through Ti(III) Catalyzed Radical Cyclization

Author(s): Antonio Rosales, Cristobal Lopez-Sanchez, Miriam Alvarez-Corral, Manuel Muooz-Dorado, Ignacio Rodriguez-Garcia.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 8 , 2007

Become EABM
Become Reviewer

Abstract:

A concise total synthesis of the furano-sesquiterpene (±)-euryfuran, a bioactive metabolite from some marine sponges, is presented. The key step is a highly diastereoselective titanium (III) catalyzed radical cyclization of a farnesol epoxyderivative.

Keywords: Titanium, radical reactions, cyclization, diastereoselectivity, farnesol, furanosesquiterpenes

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 4
ISSUE: 8
Year: 2007
Page: [553 - 555]
Pages: 3
DOI: 10.2174/157017807782795457
Price: $58

Article Metrics

PDF: 5