Excellent Exo/Endo-Selectivity in the 1,3-Dipolar Cycloaddition of Cyclic Azomethine Ylide: Exploring the Facile Investigation of Cocaine Antagonists

Author(s): Joydev K. Laha.

Journal Name: Letters in Organic Chemistry

Volume 4 , Issue 8 , 2007

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High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozers camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.

Keywords: Cocaine antagonists, tropane, 1,3-dipolar cycloaddition, cyclic azomethine ylide, exo/endo-selectivity

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Article Details

Year: 2007
Page: [550 - 552]
Pages: 3
DOI: 10.2174/157017807782795448
Price: $58

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