Abstract
Sleep deprivation and sleep disruption have long been associated with mood disorders, both as a cause as well as an effect. Sleep-disordered breathing results in significant and persistent sleep disruption, which in turn leads to significant neurocognitive deficits [1,2] and major depression [3-6]. Various pathophysiologic mechanisms may play a role in modulating mood changes in these patients. Treatment for sleep-disordered breathing often improves mood [4, 7], though the data may suggest a placebo response [8]. Patients with sleep-disordered breathing should be carefully screened for mood disorders, and patients with major depression should be screened for possible underlying sleep-disordered breathing.
Keywords: Depression in OSA, sleep and depression, OSA and mood disorder, OSA and sleep disruption
Current Respiratory Medicine Reviews
Title: Depression in Sleep Related Breathing Disorder
Volume: 3 Issue: 4
Author(s): Shyam Subramanian, Mary Rose and Salim Surani
Affiliation:
Keywords: Depression in OSA, sleep and depression, OSA and mood disorder, OSA and sleep disruption
Abstract: Sleep deprivation and sleep disruption have long been associated with mood disorders, both as a cause as well as an effect. Sleep-disordered breathing results in significant and persistent sleep disruption, which in turn leads to significant neurocognitive deficits [1,2] and major depression [3-6]. Various pathophysiologic mechanisms may play a role in modulating mood changes in these patients. Treatment for sleep-disordered breathing often improves mood [4, 7], though the data may suggest a placebo response [8]. Patients with sleep-disordered breathing should be carefully screened for mood disorders, and patients with major depression should be screened for possible underlying sleep-disordered breathing.
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Cite this article as:
Subramanian Shyam, Rose Mary and Surani Salim, Depression in Sleep Related Breathing Disorder, Current Respiratory Medicine Reviews 2007; 3 (4) . https://dx.doi.org/10.2174/157339807782359968
DOI https://dx.doi.org/10.2174/157339807782359968 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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