Current Rheumatology Reviews

Dr. Serena Guiducci  
Department of Biomedicine, Division of Rheumatology
University of Florence
Florence
Italy

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Pyridinoline, A Collagen Crosslink, As a Biochemical Marker for Arthritis

Author(s): Masaaki Takahashi.

Abstract:

Pyridinoline is a crosslink synthesized in collagen that has generally been used as a biochemical marker for bone metabolism. In addition, as pyridinoline is more abundant in cartilage and synovium than in the other tissues, there is extensive literature describing pyridinoline as a biochemical marker for cartilage destruction and metabolism, or arthritis. This paper will review the use of pyridinoline as a biochemical marker for arthritis.

Keywords: Deoxypyridinoline, urinary pyridinoline, Collagen, osteoarthritis, Ankylosing Spondylitis

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Article Details

VOLUME: 3
ISSUE: 4
Year: 2007
Page: [252 - 260]
Pages: 9
DOI: 10.2174/157339707782409017
Price: $58