Pyridinoline, A Collagen Crosslink, As a Biochemical Marker for Arthritis
Pyridinoline is a crosslink synthesized in collagen that has generally been used as a biochemical marker for bone metabolism. In addition, as pyridinoline is more abundant in cartilage and synovium than in the other tissues, there is extensive literature describing pyridinoline as a biochemical marker for cartilage destruction and metabolism, or arthritis. This paper will review the use of pyridinoline as a biochemical marker for arthritis.
Keywords: Deoxypyridinoline, urinary pyridinoline, Collagen, osteoarthritis, Ankylosing Spondylitis
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