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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Fullerenes in Medicinal Chemistry and their Biological Applications

Author(s): N. Tagmatarchis and H. Shinohara

Volume 1, Issue 4, 2001

Page: [339 - 348] Pages: 10

DOI: 10.2174/1389557013406684

Price: $65

Abstract

The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry. Pharmaceutical and biological studies have revealed that fullerene-based compounds exhibit various types of biological activity either in vitro or in vivo and are discussed in this review.

Keywords: Fullerenes, UV-Visible absorption, Photodynamic Therapy, Enzymatic Inhibition, Cell signaling, Apoptosis, Neuroprotective antioxidants, Endohedral Metallofullerenes, MRI contrast agents


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