Fullerenes in Medicinal Chemistry and their Biological Applications

Author(s): N. Tagmatarchis, H. Shinohara.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 1 , Issue 4 , 2001

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Abstract:

The isolation and preparation ten years ago of the fullerenes in bulk quantities, sparked off a truly remarkable interdisciplinary research activity, encompassing diverse fields of chemistry, physics, materials science and medicinal chemistry. Pharmaceutical and biological studies have revealed that fullerene-based compounds exhibit various types of biological activity either in vitro or in vivo and are discussed in this review.

Keywords: Fullerenes, UV-Visible absorption, Photodynamic Therapy, Enzymatic Inhibition, Cell signaling, Apoptosis, Neuroprotective antioxidants, Endohedral Metallofullerenes, MRI contrast agents

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Article Details

VOLUME: 1
ISSUE: 4
Year: 2001
Page: [339 - 348]
Pages: 10
DOI: 10.2174/1389557013406684
Price: $58

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