Therapeutic Applications of Sugar-Mimicking Glycosidase Inhibitors

Author(s): Naoki Asano, Atsushi Kato, Alison A. Watson.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 1 , Issue 2 , 2001

Abstract:

Sugar-mimicking alkaloids inhibit the glycosidases involved in a wide range of important biological processes, principally owing to their structural resemblance to the sugar moiety of the natural substrate. The possibility of modifying and blocking these processes by using such inhibitors for therapeutic applications has attracted a lot of attention.

Keywords: Glycosidase Inhibitors, glycosidases, Castanospermine, Castanospermum australe, glucosidase inhibitors, Casuarina equisetifolia, Actinoplanes, antidiabetic agents, MANNOSIDASE INHIBITORS

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 1
ISSUE: 2
Year: 2001
Page: [145 - 154]
Pages: 10
DOI: 10.2174/1389557013407052
Price: $58

Article Metrics

PDF: 2