Synthesis of Alkyl and Aryl Esters of N-Protected β-Homoamino Acids from N-Protected α-Aminodiazoketones

Author(s): G. R. Vasanthakumar, H. N. Gopi, V. Suresh Babu.

Journal Name: Protein & Peptide Letters

Volume 9 , Issue 6 , 2002

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Abstract:

A simple and concomitant esterification method for the synthesis of methyl, ethyl, t-butyl, benzyl, and 9-fluorenylmethyl esters of Fmoc- / Boc- / Z-β-homoamino acids employing Fmoc- / Boc- / Z-α- aminodiazoketones by Wolff rearrangement is described. The method offers good yield with purity.

Keywords: ALKYL, ARYL ESTERS, homoamino acids, AMINODIAZOKETONES

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Article Details

VOLUME: 9
ISSUE: 6
Year: 2002
Page: [529 - 532]
Pages: 4
DOI: 10.2174/0929866023408364
Price: $58

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