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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Evaluation and Development of Spinosyns to Control Ectoparasites on Cattle and Sheep

Author(s): Herbert A. Kirst, Lawrence C. Creemer, Sharon A. Naylor, Paul T. Pugh, Daniel E. Snyder, Joseph R. Winkle, L. Barry Lowe, James T. Rothwell, Thomas C. Sparks and Thomas V. Worden

Volume 2, Issue 7, 2002

Page: [675 - 699] Pages: 25

DOI: 10.2174/1568026023393615

Price: $65

Abstract

The spinosyns are a novel family of fermentation-derived natural products that exhibit potent insecticidal activities. Spinosad, a naturally-occurring mixture of spinosyn A and spinosyn D, has successfully established its utility for crop protective applications in the agrochemical field. Potential applications of this unique chemical family of macrolides also have been investigated in the field of animal health. Applications for the control of blowfly strike and lice on sheep have now been commercially developed and registered in Australia and potential applications for the control of ectoparasites on cattle are being studied.

Keywords: ectoparasite, spinosyns, insecticide, spinosad, macrolide


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