Towards Alzheimers Disease Vaccination

Author(s): Beka Solomon .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 2 , Issue 1 , 2002

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Abstract:

Active and passive immunization against fibrillar β-amyloid of various mice models of Alzheimers disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-β-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimers disease.

Keywords: Alzheimers Disease, EFRH-phage, Poly-L-lysine

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Article Details

VOLUME: 2
ISSUE: 1
Year: 2002
Page: [85 - 92]
Pages: 8
DOI: 10.2174/1389557023406575

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