Abstract
Active and passive immunization against fibrillar β-amyloid of various mice models of Alzheimers disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-β-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimers disease.
Keywords: Alzheimers Disease, EFRH-phage, Poly-L-lysine
Mini-Reviews in Medicinal Chemistry
Title: Towards Alzheimers Disease Vaccination
Volume: 2 Issue: 1
Author(s): Beka Solomon
Affiliation:
Keywords: Alzheimers Disease, EFRH-phage, Poly-L-lysine
Abstract: Active and passive immunization against fibrillar β-amyloid of various mice models of Alzheimers disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-β-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimers disease.
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Cite this article as:
Solomon Beka, Towards Alzheimers Disease Vaccination, Mini-Reviews in Medicinal Chemistry 2002; 2 (1) . https://dx.doi.org/10.2174/1389557023406575
DOI https://dx.doi.org/10.2174/1389557023406575 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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