Effects of Stereochemistry of Sugars on Protein Stabilities

Author(s): Kiyonari Masumoto, Tadashi Ueda, Makiko Nagata, Yuko Yamada, Yuichiro Yoshida, Yoshio Hashimoto, Taiji Imoto.

Journal Name: Protein & Peptide Letters

Volume 9 , Issue 5 , 2002

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Abstract:

We investigated thermal stabilities of four proteins in the presence of four kinds of sugars to analyze the mechanism of stabilization of proteins by additives. These proteins were stabilized by the addition of sugars, and the degree of stabilization correlated to the partial molar isentropic compressibility of the sugar.

Keywords: STEREOCHEMISTRY, molar isentropic, thermophile, polyols, lysozyme, exothermic reactions

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Article Details

VOLUME: 9
ISSUE: 5
Year: 2002
Page: [435 - 439]
Pages: 5
DOI: 10.2174/0929866023408553
Price: $58

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