The Prevention of Preterm Labour - Corticotropin Releasing Hormone Type 1 Receptors as a Target for Drug Design and Development

Author(s): P. A. Keller, K. Kirkwood, J. Morgan, S. Westcott, A. McCluskey.

Journal Name:Mini-Reviews in Medicinal Chemistry

Volume 3 , Issue 4 , 2003

Abstract:

The role of the corticotropin releasing hormone in the onset of labour and the subsequent medicinal chemistry implications of CRH antagonists for the prevention of premature birth, and identification of the CRH type 1 receptor as the target for this drug design, are reviewed here.

Keywords: Corticotropin Releasing Hormone (CRH),, premature birth, antagonists

Rights & PermissionsPrintExport

Article Details

VOLUME: 3
ISSUE: 4
Year: 2003
Page: [295 - 303]
Pages: 9
DOI: 10.2174/1389557033488105
Price: $58