Biological Properties and Therapeutic Potential of Bilirubin

Author(s): Ross P. McGeary, Alexander J. Szyczew, Istvan Toth.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 3 , Issue 3 , 2003

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Abstract:

Bilirubin was long considered a useless metabolite of heme catabolism, responsible for the clinical manifestation of jaundice, and potentially toxic in high doses, particularly in neonates. In the past two decades the potent biological properties of bilirubin, particularly as an antioxidant, have been recognised, and this has prompted a number of investigations into this molecule concerning its in vitro and in vivo properties. This review summarises that work, as well as more recent investigations into the potential therapeutic uses of bilirubin.

Keywords: Bilirubin, jaundice, antioxidant

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Article Details

VOLUME: 3
ISSUE: 3
Year: 2003
Page: [253 - 256]
Pages: 4
DOI: 10.2174/1389557033488213
Price: $58

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