Systemic Lupus Erythematosus and Other Autoimmune Diseases from Endogenous and Exogenous Agents: Unifying Theme of Oxidative Stress

Author(s): Peter Kovacic, Jason D. Jacintho.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 3 , Issue 6 , 2003

Become EABM
Become Reviewer


Extensive evidence supports oxidative stress (OS) via endogenous and exogenous agents as an important factor in induction of autoimmunity. OS arises from the immune system and other endogenous sources. The literature contains support for OS involvement of various drugs and other exogenous substances that produce the condition. Studies reveal prevention or amelioration by antioxidants.

Keywords: systemic lupus erythematosus, autoimmunity, xenobiotics, oxidative stress, antioxidants.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2003
Page: [568 - 575]
Pages: 8
DOI: 10.2174/1389557033487926
Price: $58

Article Metrics

PDF: 4