Plant-derived Terpenoids and Analogues as Anti-HIV Agents

Author(s): Kuo-Hsiung Lee.

Journal Name: Current Topics in Medicinal Chemistry

Volume 3 , Issue 2 , 2003

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Abstract:

The plant-derived terpenoids and analogues are reviewed with respect to their anti-HIV activity, structure-activity relationships, and mechanism of action. The active compounds include diterpenoid lactones, phenolic diterpenes, atisane and kaurane diterpenes, phorbol diterpenes, triterpene glycosides, friedelane triterpenes, taraxerane triterpenes, ursane triterpenes, lanostane triterpene, lupane triterpenes, seco-ring A triterpenes, degraded triterpenes, and cucurbitacin triterpenes. Positive new leads for drug development will be highlighted.

Keywords: Terpenoids, lanostane, triterpene glycosides, ursane, lupane triterpenes, cucurbitacin, taraxerane

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Article Details

VOLUME: 3
ISSUE: 2
Year: 2003
Page: [155 - 169]
Pages: 15
DOI: 10.2174/1568026033392435
Price: $58

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