A series of new potential anticonvulsants have been synthesized. They are N-methyl benzylamides of N-methyl Asp and N-methyl Glu (R and S), benzylamides of some heterocyclic acids and their Noxides and benzylamides of two heteroalicyclic acids. The obtained compounds were evaluated in the Anticonvulsant Screening Project (ASP) of Antiepileptic Drug Development Program (ADDP) of NIH.
Keywords: anticonvulsants, n-methyle-glu, n-methyl-asp derivatives, heterocyclic acid derivaties
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