Synthesis Of Retro Acyl Carrier Protein (74-65) Fragment On A New Glycerol Based Polystyrene Support

P.   G.   Sasikumar; K.   S.   Kumar; V.   N.   Rajasekharan Pillai

Abstract

Retro-ACP (74-65) fragment was synthesized on a novel 4% tri-(propylene glycol) glycerolate diacrylate cross-linked polystyrene (PS-TRPGGDA) support. The peptide is grown from the functional site present in the cross-linker, which makes it unique and cost-effective among other styrene based polymer supports. A comparative study with Merrifield resin indicates high yield and purity of the peptide synthesized on the novel support.

Keywords: glycerol based support, ps-trpggda, swelling studies, retro acp, difficult sequence

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Protein & Peptide Letters

Title: Synthesis Of Retro Acyl Carrier Protein (74-65) Fragment On A New Glycerol Based Polystyrene Support

Volume: 10 Issue: 5

Author(s): P. G. Sasikumar, K. S. Kumar and V. N. Rajasekharan Pillai

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Keywords: glycerol based support, ps-trpggda, swelling studies, retro acp, difficult sequence

Abstract: Retro-ACP (74-65) fragment was synthesized on a novel 4% tri-(propylene glycol) glycerolate diacrylate cross-linked polystyrene (PS-TRPGGDA) support. The peptide is grown from the functional site present in the cross-linker, which makes it unique and cost-effective among other styrene based polymer supports. A comparative study with Merrifield resin indicates high yield and purity of the peptide synthesized on the novel support.

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Sasikumar G. P., Kumar S. K. and Rajasekharan Pillai N. V., Synthesis Of Retro Acyl Carrier Protein (74-65) Fragment On A New Glycerol Based Polystyrene Support, Protein & Peptide Letters 2003; 10 (5) . https://dx.doi.org/10.2174/0929866033478753