Synthesis Of Retro Acyl Carrier Protein (74-65) Fragment On A New Glycerol Based Polystyrene Support

Author(s): P. G. Sasikumar, K. S. Kumar, V. N. Rajasekharan Pillai.

Journal Name: Protein & Peptide Letters

Volume 10 , Issue 5 , 2003

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Retro-ACP (74-65) fragment was synthesized on a novel 4% tri-(propylene glycol) glycerolate diacrylate cross-linked polystyrene (PS-TRPGGDA) support. The peptide is grown from the functional site present in the cross-linker, which makes it unique and cost-effective among other styrene based polymer supports. A comparative study with Merrifield resin indicates high yield and purity of the peptide synthesized on the novel support.

Keywords: glycerol based support, ps-trpggda, swelling studies, retro acp, difficult sequence

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Article Details

Year: 2003
Page: [427 - 433]
Pages: 7
DOI: 10.2174/0929866033478753
Price: $58

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