Syntheses and Biological Activities of Novel N-tert-butyl-N-Alkoxycarbonyl- N-Substituted Benzoylhydrazines and their Derivatives

Author(s): Qingmin Wang, Runqiu Huang.

Journal Name: Letters in Organic Chemistry

Volume 1 , Issue 1 , 2004

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A series of novel N-tert-butyl-N-alkoxycarbonyl-N-substitutedbenzoylhydrazines and their derivatives were synthesized. The results of bioassay showed that these title compounds exhibit moderate larvicidal activities, and toxicity assays indicated that these title compounds can induce a premature, abnormal and lethal larval molt. At the same time, we found by chance that these title compounds possess potential anticancer activities in vitro.

Keywords: alkoxycarbonyl, substitutedbenzoylhydrazines, n-tert-butyl-n-benzoyl- hydrazine, insect growth regulators, anticancer activities

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Article Details

Year: 2004
Page: [93 - 98]
Pages: 6
DOI: 10.2174/1570178043488770

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