Synthesis of N-Aryl Indolines from 2-Fluorobenzaldehyde Dimethylhydrazone Derivatives: Approach to Preparation of C(aryl)-N(Amine) Bond Atropisomeric Amines

Author(s): Takashi Mino, Youichi Tanaka, Youtaro Hattori, Motoko Tanaka, Masami Sakamoto, Tsutomu Fujita.

Journal Name: Letters in Organic Chemistry

Volume 1 , Issue 1 , 2004

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Abstract:

2-(1-indolinyl)benzaldehyde dimethylhydrazones are prepared by nucleophilic aromatic substitution of the corresponding 2-fluorobenzaldehyde dimethylhydrazones with lithiated indoline in good yields.

Keywords: hydrazone, indoline, nucleophilic aromatic substitution, atropisomer, aminophosphine

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Article Details

VOLUME: 1
ISSUE: 1
Year: 2004
Page: [67 - 69]
Pages: 3
DOI: 10.2174/1570178043488699

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