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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of N-Aryl Indolines from 2-Fluorobenzaldehyde Dimethylhydrazone Derivatives: Approach to Preparation of C(aryl)-N(Amine) Bond Atropisomeric Amines

Author(s): Takashi Mino, Youichi Tanaka, Youtaro Hattori, Motoko Tanaka, Masami Sakamoto and Tsutomu Fujita

Volume 1, Issue 1, 2004

Page: [67 - 69] Pages: 3

DOI: 10.2174/1570178043488699

Abstract

2-(1-indolinyl)benzaldehyde dimethylhydrazones are prepared by nucleophilic aromatic substitution of the corresponding 2-fluorobenzaldehyde dimethylhydrazones with lithiated indoline in good yields.

Keywords: hydrazone, indoline, nucleophilic aromatic substitution, atropisomer, aminophosphine


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