Immunotoxins and Neuropeptide-Toxin Conjugates Experimental Applications

Author(s): Dougles A. Lappi , Ronald G. Wiley .

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 4 , Issue 5 , 2004

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Abstract:

The use of targeted toxins in research applications has recently grown considerably. The ability to remove a few specific cells, even when surrounded by different populations, has given scientists a powerful tool for the understanding of systems biology. The use of targeted toxins in research is rich and varied; here we limit ourselves to describe some of those exciting results that researchers have made in the neurosciences.

Keywords: immunotoxin, ligand-toxin, peptide-toxin, saporin, retrograde transport, behavior, molecular surgery, molecular neurosurgery

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Article Details

VOLUME: 4
ISSUE: 5
Year: 2004
Page: [585 - 595]
Pages: 11
DOI: 10.2174/1389557043403882
Price: $58

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