Mini-Reviews in Medicinal Chemistry

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Immunotoxins and Other Conjugates: Pre-clinical Studies

Author(s): A. Bolognesi, L. Polito.

Abstract:

A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.

Keywords: ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy

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Article Details

VOLUME: 4
ISSUE: 5
Year: 2004
Page: [563 - 583]
Pages: 21
DOI: 10.2174/1389557043403864
Price: $58