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Mini-Reviews in Medicinal Chemistry
ISSN (Print): 1389-5575
ISSN (Online): 1875-5607
VOLUME: 4
ISSUE: 5
DOI: 10.2174/1389557043403864      Price:  $58









Immunotoxins and Other Conjugates: Pre-clinical Studies

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Author(s): A. Bolognesi and L. Polito
Pages 563-583 (21)
Abstract:
A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.
Keywords:
ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy
Affiliation:
Department of Experimental Pathology, University of Bologna, Italy