Mini-Reviews in Medicinal Chemistry

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Immunotoxins and Other Conjugates: Preparation and General Characteristics

Author(s): Giulio Fracasso, Giuseppe Bellisola, Deborah Castelletti, Giuseppe Tridente and Marco Colombatti

Affiliation: Section of Immunology, Department of Pathology, University of Verona, Italy

Abstract:

Targeted toxins represent an invaluable tool offering a wide range of potential applications, both in experimental models and in the clinics. Here we will review several aspects related to the preparation and properties of carrier molecule-toxin heteroconjugates and fusion toxins.

Keywords: toxins, ribosome inactivating proteins, immunotoxins, targeting

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Article Details

VOLUME: 4
ISSUE: 5
Page: [545 - 562]
Pages: 18
DOI: 10.2174/1389557043403909
Price: $58